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Unit confusion is the most common reconstitution error

Some early work reported favorable effects on fat metabolism, while larger later trials did not produce the weight loss outcomes needed for approval as an obesity drug

Early human trials in people with obesity found that daily AOD9604 was well tolerated and had a safety profile similar to placebo, with no major effects on glucose metabolism or IGF1, though weightloss results were modest and inconsistent

Trial REDEFINE 3 (ongoing) Phase 3 Duration Event-driven Population (N) Adults with cardiovascular disease Key Result Cardiovascular outcomes readout pending

Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma