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Avoid smoking and excessive alcohol consumption, as these can deplete glutathione levels
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Neutrophilia causes excessive ROS production that aggravates the host immunopathological response, leading to a more severe disease (Laforge et al., 2020)
In addition to vaso-occlusion, anemia, and hemolysis, SCD is now understood to be a condition that also involves increased inflammation, oxidative stress, hypercoagulability, and issues with arginine metabolism [32]
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