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Pierret ACS, Mizuno Y, Saunders P, Lim E, De Giorgi R, Howes OD, McCutcheon RA, McGowan B, Sen Gupta P, Smith D, Ismail K, Pillinger T (2025) Glucagon-Like Peptide 1 Receptor Agonists and Mental Health: A Systematic Review and Meta- Analysis
Your hair and nails may feel stronger, and your joint health should feel more stable
In the Phase 3 trial of once-weekly semaglutide for weight loss, lean body mass decreased, but the proportion of lean body mass relative to total body mass with semaglutide remained stable (earlier trials of 3.0 mg liraglutide did not report lean body mass proportions)
These benefits are thought to come from weight loss, better insulin control, and possibly direct effects on how the ovaries and brain regulate hormones
As a drug belonging to the GLP-1 receptor agonist class, it works by mimicking the action of a natural hormone in the body called glucagon-like peptide-1 (GLP-1)
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