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Research comparing the two has shown that copper chelation generally enhances the biological activity of the peptide, particularly for collagen-stimulating and angiogenic effects

R-lipoic acid is the natural form found in the human body and in plants

Further, if confirmed, the improvement in these molecular mechanisms can lead to important clinical implications in vitiligo phenotypic traits and disease prognostic, that ultimately, may improve patients self-image, body confidence, and reduce psychological distress associated with this disease ( The literature has shown that chronic PE plays a significant role in EAS enzymatic metabolism, IS modulation, and mitochondrial quality and function

Dupin et al., 2012

Its activity is associated with signaling networks involved in blood vessel formation and maintenance, which are essential during the early stages of tissue recovery