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Haines M, et al
Lipogenesis Inhibition: In adipose tissue, NNMT inhibition reduces lipid accumulation by up to 70% (in vitro), shifting the cell's priority from fat storage to energy expenditure
Moving toward a systems-level understanding, empowered by interactomics, CRISPR technologies, AI-driven modeling and precision biomarker science, will profoundly transform how we interpret disease biology and develop therapeutics
doi: 10.1007/s10295-019-02203-4 120 MerensteinDPotBLeyerGOuwehandACPreidisGAElkinsCAet al
Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs), initially developed for diabetes and obesity, exhibit pleiotropic effectsincluding anti-inflammatory, antioxidant, and neuroprotective propertiesthat position them as transformative candidates for ocular therapeutics
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