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For most patients, the diarrhea is manageable and transient and many actually prefer it to nausea
They can be used in patients with an estimated glomerular filtration rate over 15 mL/min/1.73 m 2
Indeed, both in rodents and humans, GLP-1 infusion increased fractional sodium excretion [20], which has been linked to the finding that sodium is more rapidly excreted following an oral versus equivalent IV sodium load in a number of experimental studies in healthy individuals, independent of factors such as atrial natriuretic peptide (ANP) and aldosterone [22]
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99,287 Furthermore, elevated uric acid levels have been implicated in causing inflammation in endothelial cells via the activation of the receptor for advanced glycation end products (RAGE) signaling pathway
O.AarestrupB
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