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GGsTop activity remained stable in water at room temperature (Extended Data Fig

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Minimal response may warrant increasing by 50-100mcg

Because glutamate signalling is ubiquitous in the brain (and concentrated in other tissues such as the heart, adrenal glands and the gastrointestinal tract Julio-Pieper et al 2011) this neuroinflammatory cycle can result in a wide range of symptoms that then result in a variety of differential diagnoses