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A population of SAM with distinct transcriptional signatures has also been reported in the hippocampus of SDS models, enriched for cytokine/chemokine signaling, cellular stress, and phagocytic activity (Goodman et al., 2024)

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estimated free phenytoin level (from the total level) estimated free phenytoin level (from the total level) The most accurate equation to estimate the free phenytoin in critically ill patients appears to be the Barra equation: (32049893) Estimated Free phenytoin = 1.69 +0.139(Total phenytoin in mcg/ml) -0.008(Age) -0.424(Albumin in g/dL) +0.01(BUN in mg/dL) +0.288 [Critically Ill (yes, 1

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Glutathione treatment also decreased protein-bound glutathione to normal baseline levels

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