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Reduces senescence-associated secretory phenotype burden: Senescent cells secrete inflammatory cytokines, chemokines, growth factors, and proteases collectively referred to as the senescence-associated secretory phenotype (SASP)
For instance, pairing subcutaneous injections with topical products or microneedling can maximize both systemic and localized benefits for skin and hair
No clinical trials in humans have established short or long-term safety
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Current pharmacological strategies for UC primarily include 5-aminosalicylic acid (5-ASA), glucocorticoids, thiopurines, biological medications, and anti-cytokine therapies (Lamb et al., 2019
