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What they did: Review article by two founders of melanocortin therapeutics
Nausea Diarrhea Decreased appetite Vomiting Constipation Dyspepsia (indigestion) Abdominal pain Injection-site reactions Fatigue Pancreatitis Gallbladder disease (cholelithiasis, cholecystitis) Acute kidney injury (usually from dehydration via GI fluid loss) Hypoglycemia (mainly when combined with insulin or a sulfonylurea) Diabetic retinopathy complications Hypersensitivity reactions Thyroid C-cell tumours (boxed warning
I was tired all the time
Generation 1 Single agonist (GLP-1 only): Drugs like semaglutide (sold as Ozempic for diabetes and Wegovy for weight loss) target one receptor: GLP-1
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