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Buteau J, Roduit R, Susini S, Prentki M (1999) Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
Side effects may include scalp irritation or hormonal changes
In the recent DREAM (Diabetes REduction AssessMent with ramipril and rosiglitazone) study, the effect of treatment with the thiazolidinedione rosiglitazone on the incidence of cardiovascular events in prediabetic individuals was assessed as a secondary endpoint
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