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Together, these findings demonstrate how enteroviruses leverage host cellular machinery, not just for replication, but for their own dissemination and immune evasion, providing a compelling picture of how these viruses, specifically CVB, may contribute to the chronic inflammation and cell destruction characteristic of T1D

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The reduced gene expression or deletion of MET in vivo in mice results in altered synapse maturation (reviewed in Autism spectrum disorder is associated with deficits in the ontogeny of neural circuits ( MET promoter region in more than 200 families with ASD (Figure 3)

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Starting at a low dose and increasing gradually helps minimize these effects

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