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With each successive cycle, anthracycline metabolites accumulate in cardiac tissue, disrupting mitochondrial function, triggering apoptosis and ultimately causing irreversible loss of contractile muscle [54, 55]
2.2.1 Flavonoids 2.2.1.1 Apigenin, acacetin and fisetin Research on the role of natural flavonoids in necroptosis is limited and has focused mainly on the RIPK family and MLKL
The upstream vs
Woodfield GW, Horan AD, Chen Y, Weigel RJ
Should we both be tested for this mutation
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