Notably, individuals with PD and coexisting metabolic comorbgidities such as insulin resistance or obesity appear to derive greater clinical and cognitive benefits from GLP-1 RA therapy [62, 63]
However, while Mounjaro focuses on glucose control in type 2 diabetes, Zepbound earned its FDA approval for addressing weight management issues, especially for adults facing obesity or related conditions like high blood pressure or elevated cholesterol
(Accessed: March 24, 2023)
The rapid onset of benefit from SGLT2 inhibitors suggests that haemodynamic and metabolic improvements, rather than structural reverse remodelling, drive early risk reduction
Tirzepatide Update: In a surprisingly + legal development, an ex parte response was submitted yesterday in the ongoing lawsuit over Tirzepatide