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10 January 2023
declare that they have no competing interests in this work
OCTN2 dysfunction causes systemic primary carnitine deficiency (SPCD), a potentially lethal disorder
some patients will lose more, some will lose less, and some may discontinue treatment altogether because of side effects
For patients requiring injectable therapy with cardiovascular or renal benefits, SGLT2 inhibitors (sodium-glucose co-transporter-2 inhibitors) such as empagliflozin, dapagliflozin, or canagliflozin offer an alternative mechanism of action with proven cardiovascular and renoprotective effects
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