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Higher doses increased the incidence of rib malformations in offspring at 1000 mg/kg, or approximately 100 times human exposure at the MRHD

Obesity treatment needs to be thought of the same way

Given this common developmental lineage, Schwann cells may be capable of synthesizing melanin under specific circumstances (52)

References Pickart, L., & Margolina, A

It's worth noting that early in treatment, nausea and other gastrointestinal side effects may contribute to reduced food appeal, though the appetite-suppressing effects persist even as these side effects typically diminish with continued therapy