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I felt like I was a gear that always kind of had a weird clunk to it before, and now I just feel normal. Doctors have also seen marked improvement when they use GLP-1s to treat people with eating disordersmajor mental health conditions that hijack sufferers relationship with food

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In smaller acute metabolic studies with DPP-4 inhibitors, a reduction of the post-prandial rise in triglycerides, and apolipoprotein-B 48 was observed

The current evidence doesnt suggest you should avoid Wegovy if youre taking sertraline, but it does highlight the importance of: Continuing your prescribed antidepressant treatment Monitoring your mood, particularly in the first few months Keeping your GP informed about any changes in how youre feeling Not stopping sertraline without medical advice, even if you feel your mood has improved Practical tips for taking both medications If youre taking sertraline and starting Wegovy, here are some practical suggestions