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A novel DPP 4 inhibitor Gramcyclin A attenuates cognitive deficits in APP / PS1 /tau triple transgenic mice via enhancing brain GLP 1-dependent glucose uptake

GLP-1, a hormone primarily secreted from the ileum in response to nutrient intake, exerts multiple metabolic effects including appetite suppression, delayed gastric emptying, enhanced insulin secretion, and inhibition of glucagon release [4]

Certain vitamins when infused can alter effectiveness of calcium channel blockers, increase blood sugar, and effect INR for those on Coumadin or Warfarin treatment

Sandstrom and Sehlin, 1988c