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The in vivo effects of AT-7687 were evaluated in obese cynomolgus monkeys, and when combined with the GLP-1 analogue liraglutide, AT-7687 enhances weight reduction induced by liraglutide and improves glycemic control and lipid metabolism ( 3 Results of reduced GIP receptor activation in humans Some GIP receptor antagonists have contributed to the elucidation of the physiological properties of endogenous GIP
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