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In PD, GSH impacts the degeneration of dopaminergic neurons
Activation of glutathione peroxidase 4 as a novel anti-inflammatory strategy
It also participates in the regulation of apoptosis pathways, with HSPD1 as a representative member that is localized in the mitochondrial matrix and functions as a molecular chaperone in an ATP-dependent manner (Singh et al., 2024a)
53(4): p
It demonstrates considerable cytotoxicity, stimulates p53 expression, elevates ROS generation and lipid peroxidation, while simultaneously reducing SLC7A11 and GPX4 levels
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