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however, these factors would affect all groups equally and do not invalidate between-group comparisons

[37] As a first-line defense against constipation, I will usually recommend adding more fiber to ones diet and taking magnesium supplements

Both lipoic acid and dihydrolipoic acid have been found to inhibit copper- and iron-mediated oxidative damage in the test tube (22, 23) and to inhibit excess iron and copper accumulation in animal models (24, 25)

Formulation factors including pH, penetration enhancers, and stability protection are important considerations