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Repurposing antidiabetic drugs like GLP-1 mimetics for neurological diseases is gaining interest, as metabolic disorders pose a significant risk for neurodegeneration
Gondo et al, Growth Hormone-Releasing Peptide-2 Stimulates GH Secretion in GH-Deficient Patients with Mutated GH-Releasing Hormone Receptor, The Journal of Clinical Endocrinology & Metabolism, Volume 86, Issue 7, 1 July 2001, Pages 32793283, Mericq V, Cassorla F, Salazar T, Avila A, Iiguez G, Bowers CY, Merriam GR
Next, the time course of rebound in GSH levels after the CS exposure was examined
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Secondary objectives were change from baseline to week 3 for tirzepatide versus placebo in fasting and postprandial appetite VAS ratings, FCI, FCQ-S, Eating Inventory, PFS questionnaire ratings and BOLD activation to photos of Food HiPal (Food HiF/HiS and Food HiF/HiC ) relative to non-food during the fasting state in the prespecified principal reward ROIs
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