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It is a once-daily tablet taken on an empty stomach and, like all licensed weight-loss medicines, is prescription-only and offered after clinical assessment against BMI-based criteria as an adjunct to a reduced-calorie diet and increased physical activity
Unfortunately leptin mimetics have failed to provide significant weight loss outside the cases of leptin-replacement therapy for patients with genetic leptin deficiency [12, 13]
The GIP/GLP-1-receptor agonist tirzepatide was approved for the treatment of T2D by the Food and Drug Administration (FDA) in the USA for once-weekly subcutaneous injections in May 2022 and has just received a positive opinion from the European Medicines Agency (EMA)
Presented for research literature review only Shahmohamadi E et al
The number of sessions increases, raising the expense
