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The Institute for Clinical and Economic Review (ICER) in 2025 noted that price reductions and long-term benefits have improved GLP-1 cost-effectiveness relative to older assumptions ( [70] ), yet insurers still face high absolute spend

doi:10.1186/1477-7827-7-40 Xu Y, Nisenblat V, Lu C, et al

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Commonly, the same doses used to treat diabetes are prescribed, such as metformin 500mg or metformin modified release, but always under medical supervision

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