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As can dietary fibers
The active metabolites of Pycnogenol, particularly the smaller phenolic acids and the gut-derived metabolite M1, can enter the central nervous system
The Benoist et al
The distinction between Lipo B (vitamin-dominant, cofactor-based) and Lipo C (amino acid-dominant, lipotropic-based) matters because vitamins require immediate enzymatic incorporation while amino acids undergo delayed hepatic metabolism before utilization
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