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Notably, in these lanthanide-conjugated antibody-based assays, the conformational flexibility of the antibodies compensates for the more considerable distance between donor and acceptor, providing an abundant opportunity for energy transfer to occur during the extended detection window of the measurement, provided by the prolonged donor-excited-state lifetime 33
Interestingly, substituting the amino acids with alanine enhanced the peptides inhibitory ability (Table 1)
It is crucial to exercise caution and avoid driving or operating machinery at any level of impairment
Kornblau SM, Qiu YH, Graber G, Chen W, Melendez J, Konopleva M, Faderl S, Andreeff M , Borthakur G, Yao H, Coombes KR
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