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373 Given OPA1s role in mediating intercellular mitochondrial transfer via MDVs, 187 the ability to secrete damaged mitochondria into the extracellular space might be impaired in ADOA
siRNA targeting Pkm2 (5-CTTGCAGCTATTCGAGGAA-3) was designed by and purchased from RiboBio (Guangzhou, China)
Because a unit is a fixed volume (0.01 mL), the smallest reliably measurable mass is set jointly by the concentration and the finest graduation on the barrel
If your protocol calls for very small doses (under 50 mcg), consider 2 mL instead to make measurements more practical
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VPA has a small volume of distribution (0.130.23 l/kg) [11, 15, 16]
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