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However, insufficient research is currently available to support the role of lycopene in preventing malignant transformation of digestive lesions, thus, larger sample sizes of human clinical trials are warranted to further uncover the potential role of lycopene in preventing the malignant transformation of digestive lesions

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For example, switching from a weight-promoting antidepressant to bupropion or from a sulfonylurea to a sodium-glucose cotransporter-2 (SGLT2) inhibitor may enhance overall weight loss while maintaining therapeutic efficacy for the primary condition