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NICE NG28 and the MHRA advise considering B12 monitoring in long-term metformin users who have symptoms or risk factors for deficiency, as metformin can impair B12 absorption in the terminal ileum
6063 Additionally, a recent meta-analysis revealed that all SGLT-2is reportedly cause a weight loss of about 1.52kg in obese T2D patients, relative to placebo, and this effect is dose dependent
Cardiovascular improvements The SELECT trial gave us the biggest breakthrough yet
A multivitamin is a reasonable starting point but insufficient on its own
Cureus, [online] 17(1).
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