Tirzepatide works by activating two incretin hormones: Glucose-Dependent Insulinotropic Polypeptide (GIP): Enhances insulin secretion and has effects on fat metabolism
It is a pentapeptide, composed of five amino acids with the following structure: Aib-His-D-2-Nal-D-Phe-Lys-NH2
[14] Double-check that the pharmacy or clinic is licensed and US-based
In Singapore, GLP-1 weight loss medications are regulated prescription treatments and should only be used under proper medical supervision
Requirements usually include: (1) BMI 30 , or BMI 27 with at least one weight-related health condition (type 2 diabetes, high blood pressure, or high cholesterol per FDA labeling), (2) participation in a 6-month weight management program (diet, exercise, and lifestyle changes), (3) chart notes documenting BMI and health conditions, and (4) no contraindications such as personal/family history of medullary thyroid cancer or MEN2 syndrome (a rare genetic condition)