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Other plateau-breaking strategies to try first Before adding the complexity of medication alternating, several evidence-based strategies can help break through a GLP-1 plateau: Dose optimization
Avoid Lying Down Right After Eating After you eat, sit upright or recline gentlybut avoid lying flat
Diet: heavy alcohol use and certain nutrients can lower your B12, so you may notice effects fading sooner
Chronic stress, whether from work, relationships, financial pressure, or the frustration of weight gain itself, keeps cortisol elevated throughout the day
Use a Travel Cooler Invest in a high-quality, portable cooler designed for medications
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