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Pregnancy, breastfeeding, or plans to conceive: avoid semaglutide because of potential fetal harm
That selectivity is the single most cited property of the molecule
retail costs, making GLP-1 therapy more accessible even without insurance coverage
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)