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Cholinesterase inhibitors prescribed for dementia or mild Alzheimers disease keep acetylcholine in a neuronal synapse, as do medications treating myasthenia gravis and many eye conditions.42 Acetylcholine-influencing compounds are extremely common in nootropic supplements

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Polyamines have a widely recognized dual role: they stabilise macromolecules at low concentrations, modulate signalling and protect against stress, whereas they can actively trigger or potentiate PCD at higher concentrations