Acknowledgements The authors thank L Johnson, L Wilkins, S Bound, S Oliver, J Martin, R Meeny, N Blasch, and F Dabrowski for animal care, S Holloway and J House for veterinary care, L Potenza and C Burstrm for excellent technical assistance, and A Samson for insightful advice
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However, telomerase activation is not the same as proven lifespan extension, animal-lifespan results are mixed (one key mouse study found no increase in mean lifespan), and human data are limited and largely open-label
Typically, melasma shows up as brown or brown-gray patches
Rights and permissions About this article Cite this article Tolu, P., Masi, F., Leggio, B