Potassium plays a role in maintaining water balance within cells, favors depolarization of nerve tissues and muscle contraction, is involved in ATP production, and maintains acidbase equilibrium (4)
In contrast, the DOX group exhibited severe myocardial injury characterized by myofibrillar degeneration, cytoplasmic vacuolization, necrosis, and marked inflammatory cell infiltration
The lack of functional GSTU13 resulted in enhanced disease susceptibility toward several fungal pathogens including Erysiphe pisi, Colletotrichum gloeosporioides , and Plectosphaerella cucumerina (Pislewska-Bednarek et al., 2018)
Therefore, strict genomic screening of undifferentiated iPSCs after reprogramming is urgently needed to guarantee the safety of seeding cells (Parmar et al., 2020)
Although several studies have shown promising results with NAC, the optimal dosages remain unclear, and further research is needed to fully understand its efficacy and safety