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This pharmacokinetic profile provides a natural taper period, though patients should understand that appetite suppression and glycemic benefits will progressively decline during this window

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Speaking to MNT , Manish Mittal, MD, hair transplant surgeon at Mittal Hair Clinic, who was not involved in this study, explained that the vast majority of patients will never experience clinically significant hair loss, but the study reinforces that shedding can occur in a small proportion of people and is something clinicians should discuss before treatment. Thus, individuals taking GLP-1 medications for type 2 diabetes should be aware of all options available to them, which could include SGLT-2 inhibitors and DPP-4 inhibitors, depending on individual circumstances

However, changes in epicardial fat density, which may reflect alterations in adipose tissue biology rather than size alone, was linked to improved outcomes

The 2mg dose primarily activates GLP-1 with minimal glucagon receptor engagement