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Side Effect Profile Both medications share similar side effects, primarily because of the overlapping GLP-1 mechanism: Nausea most common, especially when starting or increasing dose Vomiting typically mild and improves over time Diarrhea or constipation varies by patient Fatigue common in the first weeks Reduced appetite the desired effect, but can lead to insufficient nutrition if not managed Does tirzepatide cause more side effects

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Furthermore, weight loss alone does not cure lymphedema, and patients require continued conservative management regardless of weight reduction

Acute pancreatitis typically manifests with severe upper abdominal pain that may radiate to the back, nausea, vomiting, and fever

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