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Epididymal fat was subjected to haematoxylin and eosin (H&E) staining, immunohistochemical (IHC) staining, TG and glycerol content per cell, and SIRT1 activity assay (see ESM Methods)
The reason why [semaglutide] works is not just the fact that it depresses appetite, its that it gets insulin to work better
Acknowledgments The authors would like to acknowledge the use of generative AI technology, specifically Scholar AI, based on OpenAI's GPT-4 architecture, for revising the grammar of this paper
In agreement with results in iWAT from mice under cold-exposure 24 or caloric restriction 50 , enrichment in eosinophils and, importantly, a rise of the IL4 + subpopulation, was found in both SVF and eWAT from G49-treated DIO mice together with elevated Il4 and Il13 gene expression, a M2 immune signature related to beiging 50
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