Clinically significant A1c reductions typically occur after 12 weeks of therapy
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The GLP-1R, widely expressed in many systems and organs, has a neuroprotective effect, supporting intracellular homeostasis and reducing damage to neurons caused by oxidative stress, inflammatory cascades, apoptotic signals, and ischemic conditions [11]
Weekly Dosing Possible Due to Long Half-Life Tirzepatide remains active in the body for several days because it has a long half-life
The principle is universal across all injectable peptides