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The more accurate description is that DSIP has been studied as a sleep architecture modulator a compound that may influence the structure and quality of sleep rather than as something that switches sleep on like a hypnotic
That said, most published studies have used injection methods, and oral bioavailability in humans has not been clinically established
The authors administered oral Dihexa to APP/PS1 transgenic mice (a standard amyloidopathy model of Alzheimers disease) and showed that brain AngIV levels were elevated relative to wild-type after Dihexa administration, that spatial learning and memory were restored on Morris water maze testing, that hippocampal neuronal density and synaptophysin protein expression were preserved, that astrocyte and microglial activation were reduced, and that pro-inflammatory cytokines (IL-1, TNF-) decreased while anti-inflammatory IL-10 increased
Whether to use peptides is ultimately a decision between a patient and a physician
Glutathione S-transferases and prevention of cellular free radical damage [PMID: 9736316] Laboratory literature summary: Glutathione S-transferases and prevention of cellular free radical damage
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