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PloS One (2011) 6(8):e23205

He P, Li H, Yang Z, Zhang R, Ye Q, Deng T, et al

The gut-brain axis: challenging the old GLP-1 model The original theory was simple: food enters the gut the gut releases GLP-1 GLP-1 travels via the bloodstream into the brain GLP-1 induces more GLP-1 release within the brain appetite is suppressed