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Recent metanalysis have revealed significant increase in oxidative stress markers such as MDA and a substantial depletion of antioxidants such as catalase, GSH in the blood, and postmortem brain of PD patients compared to healthy controls 25

Disease Management and Clinical Outcomes , 1, 136-141

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Bethany Tennant, N.D., C.N.S., is a licensed naturopathic physician and certified nutrition specialist

1115,1116 Oligonucleotides and small interfering RNAs (siRNAs) modulate pre-mRNA splicing or neutralize microRNAs, increasing the expression of energy-producing genes that are often downregulated in neurodegenerative conditions