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A stable, cold environment is crucial

Furthermore, limited diagnostic capabilities, difficulty in identifying eligible patients, and variability in disease progression collectively contribute to low enrollment rates, prolonged study timelines, and compromised data integrity in rare disease trials, ultimately resulting in higher failure rates compared to non-rare disease trials 5,6

This leads to the formation of large, abnormal and immature red blood cells and impaired DNA synthesis

Select an injection site with adequate subcutaneous fat, typically the abdomen around the navel (staying 2 inches away from the navel itself), outer thighs, or back of the upper arms