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PERIOPERATIVE CONSIDERATIONS FOR GLP-1RAS AND GIP/GLP-1RA THERAPY Increased residual gastric content There is emerging evidence that the use of GLP-1 receptor agonists is associated with increased RGC, based on studies in patients undergoing endoscopy, despite fasting for at least 8 hours [68]

But this is an inconclusive result, he says

Based on these findings, Lilly plans to submit regulatory applications in the second half of 2026 for: Chronic weight management Knee osteoarthritis pain associated with obesity Moderate-to-severe obstructive sleep apnea The company also expects to submit a regulatory application for the treatment of type 2 diabetes in 2027

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It is one compound in a rapidly expanding class of GLP-1-based peptides, and understanding where it sits in that landscape helps researchers make informed protocol decisions