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One of the ways it does this is by slowing emptying of the stomach so there is a feeling of satiety
Intranasal administration of Ex-4 at a dose of 0.5 g/kg daily for 7 days before MCAO in mice, rather than intraperitoneal administration at an equivalent dose, exerted neuroprotective effect by reducing infarct volume and neurological deficits which were blocked by knocking down GLP-1 receptor with shRNA (136)
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It belongs to a novel class of agents known as triple receptor agonists , meaning it simultaneously activates three distinct hormone receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor
