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Because there is not enough high-quality human evidence to support routine clinical use and they are not currently approved for use in Humans by Health Canada or the FDA
As we age, tendons stiffen, gut barrier function deteriorates, wound healing slows, and chronic low-grade inflammation ("inflammaging") erodes organ function
Lambert, M
Ectopic expression of HA-tagged PDS5B led to a robust increase in the number of SIRF foci upon HU treatment, indicative of enhanced recruitment of PDS5B to stressed replication forks
But virally
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