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Martinowich, K
In laboratory models, the compound has been associated with upregulation of the nitric oxide (NO) system, modulation of vascular endothelial growth factor receptor 2 (VEGFR2), and activation of focal adhesion kinase (FAK) pathways implicated in angiogenesis, cell migration, and tissue repair
NPI-001 depleted cystine from human cystinosis fibroblast cells in culture statistically significantly greater than cysteamine
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