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Epitalon: A pineal-derived peptide shown to regulate melatonin and telomerase activity, supporting circadian rhythm and cellular longevity

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Activation of GLP-1R attenuated CM-associated mechanical allodynia Considering the significant upregulation of GLP-1R in the TNC and the widely recognized effect of microglia in CM, it is reasonable to expect that GLP-1R may play an important role in the pathogenesis of CM

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The scientific rationale for the combination is derived from: (1) Ipamorelin pharmacology demonstrating GHSR-1a selective GH stimulation (Raun et al

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