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The standard research protocol is 300 mcg per day, subcutaneous, administered in a fasted state, typically in the morning before food or exercise
If your vitamin deficiency is caused by malabsorption of B12 from food , your doctor might recommend B12 shots
Many report noticeable improvements in energy and mood within 2472 hours
Patients should be educated about warning signs requiring immediate medical attention, including severe abdominal pain (potential pancreatitis or gallbladder disease), persistent vomiting, dark urine, or yellowing of skin or eyes
Started early, some patients may fully recover
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