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We and others also demonstrated that hemin induces the expression of NRF2 in SCD erythroblasts and animal models and such effect is mitigated by administration of dimethyl fumarate (DMF) 23,24 , an FDA-approved drug for the treatment of multiple sclerosis
Body composition effects One concern with any rapid weight loss intervention is the loss of lean mass alongside fat mass
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[1] [2] Because the drug is not yet licensed, all information regarding its side effects, including long-term risks, is derived from clinical trial data rather than post-marketing surveillance
